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Ceftin (Cefuroxime)
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Ceftin

Ceftin is used for treating bacterial infections (sinus, skin, lung, urinary tract, ear, and throat). It may also be used to treat Lyme disease and gonorrhea.

Other names for this medication:
Ceftum, Zocef, Cefakind, Supacef, Altacef, C-Furo, Oratil, Stafcure, Pulmocef, Zefu, Ceftin, Kefurox, Zinacef, Zinacef ADD-Vantage, Zinacef TwistVial

Similar Products:
Lorabid, Cefotan, Cefzil, Lorabid Pulvules, Mefoxin, Raniclor

 

Also known as:  Cefuroxime.

Description

Ceftin is a cephalosporin antibiotic. It works by interfering with the formation of the bacteria's cell wall so that the wall ruptures, resulting in the death of the bacteria.

Generic name of Ceftin is Cefuroxime.

Ceftin is also known as Cefuroxime axetil, Zinacef, Bacticef, Cefasun, Cefudura, Cefuhexal, Cefurax, Cefutil, Cetil, Froxime, Elobact, Oraxim, Zinnat.

Brand name of Ceftin is Ceftin.

Dosage

Take Ceftin by mouth with or without food.

Swallow Ceftin whole. Do not break, crush, or chew before swallowing.

Ceftin works best if it is taken at the same time each day.

If you want to achieve most effective results do not stop taking Ceftin suddenly. To clear up your infection completely, take Ceftin for the full course of treatment. Keep taking it even if you feel better in a few days.

Overdose

If you overdose Ceftin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Ceftin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Ceftin if you are allergic to Ceftin components.

Ceftin should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections.

Be careful if you are pregnant, planning to become pregnant, or are breast-feeding.

Be careful if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.

Be careful if you are diabetes patient. Ceftin may cause the results of some tests for urine glucose to be wrong.

To prevent pregnancy, use an extra form of birth control because hormonal birth control pills may not work as well while you are using Ceftin.

It can be dangerous to stop Ceftin taking suddenly.

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Six hundred thirty-six adults with CAP requiring hospitalization and initial IV antibiotic treatment.

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Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of community-acquired pneumonia in adults. Patients received either intravenous and/or oral levofloxacin (500 mg once daily) or the comparative agents, parenteral ceftriaxone (1 to 2 g once to twice daily) and/or oral cefuroxime axetil (500 mg twice daily). Erythromycin or doxycycline could be added to the comparator arm at the investigator's discretion. The decision to use an intravenous or oral antimicrobial agent for initial therapy was made by the investigator. Clinical and microbiological evaluations were completed at the baseline, during treatment, 5 to 7 days posttherapy, and 3 to 4 weeks posttherapy. Four hundred fifty-six patients (226 given levofloxacin and 230 administered ceftriaxone and/or cefuroxime axetil) were evaluable for clinical efficacy. Streptococcus pneumoniae and Haemophilus influenzae were isolated in 15 and 12%, respectively, of clinically evaluable patients. One hundred fifty atypical pathogens were identified: 101 were Chlamydia pneumoniae, 41 were Mycoplasma pneumoniae, and 8 were Legionella pneumophila. Clinical success at 5 to 7 days posttherapy was superior for the levofloxacin group (96%) compared with the ceftriaxone and/or cefuroxime axetil group (90%) (95% confidence interval [CI] of -10.7 to -1.3). Among patients with typical respiratory pathogens who were evaluable for microbiological efficacy, the overall bacteriologic eradication rates were superior for levofloxacin (98%) compared with the ceftriaxone and/or cefuroxime axetil group (85%) (95% CI of -21.6 to -4.8). Levofloxacin eradicated 100% of the most frequently reported respiratory pathogens (i.e., H. influenzae and S. pneumoniae) and provided a >98% clinical success rate in patients with atypical pathogens. Both levofloxacin and ceftriaxone-cefuroxime axetil eradicated 100% of the S. pneumoniae cells detected in blood culture. Drug-related adverse events were reported in 5.8% of patients receiving levofloxacin and in 8.5% of patients administered ceftriaxone and/or cefuroxime axetil. Gastrointestinal and central and peripheral nervous system adverse events were the most common events reported in each treatment group. In conclusion, these results demonstrate that treatment with levofloxacin is superior to ceftriaxone and/or cefuroxime axetil therapy in the management of community-acquired pneumonia in adults.

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Our data show that cross-reactivity between penicillins and cephalosporins may be as high as 10.9% for first-generation cephalosporins and 1.1% for third-generation cephalosporins, possibly due to the involvement of similar side chains. Patch tests are a useful diagnostic tool to assess cross-reactivity, but a graded challenge is mandatory because a negative patch test does not always mean tolerability.

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From about one-third to two-thirds of cases of pneumonia can be attributed to a specific etiology depending on which culture, antigen detection and specialized serologic techniques, some of which are unavailable to clinicians, are used. Results of studies in which microbiologic causes have been sought confirm the importance of Streptococcus pneumoniae as the primary bacterial cause of pneumonia in infants and children. Viral etiologies become less prevalent and mycoplasmal and chlamydial infections become more prevalent with increasing age.

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Out of the 29436 emergencies studied on 30 days, 821 were diagnosed with acute otitis media. Fifteen point seven percent of the cases were already receiving antibiotics (22% amoxicillin clavulanate, 20% amoxicillin and 11% cefuroxime axetil). For the treatment, at discharge, of the 93% an antibiotic was prescribed (amoxicillin clavulanate in 41%, amoxicillin in 15%, cefuroxime axetil in 11%, cefaclor 6% and azithromycin 5%). Two point eight percent of the children were admitted. According to the guidelines of the panel of experts consulted, appropriateness was 61% for antibiotics of first choice, 12% for drugs of alternate use and 25% for inadequate treatment. The different hospitals presented significant variability in the type of antibiotic used and the appropriateness of such.

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Cefuroxime axetil is an oral cephalosporin with proven efficacy in adult lower respiratory tract infections. Indeed, it has a broad spectrum of activity in vitro, covering most pathogens isolated in this setting and showing good stability in the presence of betalactamases. In vitro susceptibility data are a major element in the choice of antimicrobial agent. The aim of this study was to determine the predictive value of the cefuroxime minimal inhibitory concentration (MIC) on the clinical outcome of infections treated with cefuroxime axetil. One hundred-and-seventeen (117) patients with radiologically confirmed community-acquired pneumonia of presumed bacterial origin were enrolled in a prospective multicenter trial of cefuroxime axetil therapy (500 mg twice daily). The pathogen was identified in 44 patients who were treated for a mean of 8.8 days. Most isolates were S. pneumoniae (65.9%) and H. influenzae (15.9%). The MIC was known for 35 isolates and was < or = 4 micrograms/ml in 30 cases (85.7%). The MIC value was a good predictor of clinical efficacy with a sensitivity of 100%, a specificity of 83% and a positive predictive value of 97%; the latter value indicates that therapeutic success is virtually certain when the bacterium causing pneumonia is susceptible to cefuroxime.

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where to buy ceftin 2017-07-22

Peritonitis is one of the causes of early peritoneal dialysis (PD) failure in newly-placed catheters. Antibiotic prophylaxis has been recommended to decrease the risk buy ceftin of infection after PD catheter placement. In this study, we compared the efficacy of parenteral versus oral prophylactic cefuroxime axetil for preventing peritonitis after placed PD catheters.

buy ceftin uk 2016-10-18

Patients with AECOPD and without radiographic evidence of pneumonia were enrolled and randomized to either levofloxacin 500 mg daily or cefuroxime 250 mg twice daily in the mildmoderate exacerbation group, or Buy Amoxicillin In Usa 500 mg twice daily in the severe exacerbation group, for seven days. Clinical efficacy and microbiologic response were evaluated 5-7 days after the last dose.

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(1) The study determined the incidence of urinary tract infection in febrile infants <2 Buy Zithromax Online Australia months of age in Southern Israel; (2) E. coli was responsible for the majority of first and recurrent urinary tract infection; (3) recurrent urinary tract infection was caused mostly by pathogens different than the pathogens isolated at initial episode.

buy ceftin online 2015-09-29

To compare the efficacy of cefuroxime axetil and doxycycline in the treatment of Buy Azithromycin India patients with Lyme disease associated with erythema migrans.

buy ceftin 500mg 2016-06-17

Patients with a primary diagnosis of CAP were Buy Antibiotic Ciprofloxacin enrolled in a multicenter, prospective, randomized, open-label, active-controlled Phase III clinical trial. Both inpatients and outpatients were assigned to 1 of 2 treatment groups: (1) intravenous (i.v.) or p.o. levofloxacin; or (2) i.v. ceftriaxone and/or p.o. cefuroxime axetil.

buy ceftin 2017-04-13

The aim of this study was to analyze the dispensation of anti-infectives for systemic use, excluding immune sera and immunoglobulins and vaccines, made in all of Spain's pharmaceutical offices in a two-year period and to analyze their pharmacological cost. A retrospective pharmacoepidemiological study was made of dispensations in Spain's pharmaceutical offices for medicines belonging to the J01, J02, J04 and J05 subgroups. The dispensations were quantified as defined daily doses per 1 Buy Amoxicillin Uk Boots ,000 inhabitants per day (DID). The economic cost of the dispensing was expressed in absolute terms and as CID (cost per 1,000 inhabitants per day). The total DID of anti-infective drugs was 32.11 (30.70 for antibacterials, 0.53 antimycotics, 0.73 for antimicrobacterials and 0.16 for antivirals). In the J01 subgroup the most frequently used were penicillins, macrolides, cephalosporins and quinolones. And the most frequently used drugs were amoxicillin, amoxicillin and clavulanic acid, clarithromycin, cefuroxime axetil and ciprofloxacin. The total cost was 1,403,462,770 euros, and the CID was 47.18 euros.